A Unified Treatment of the Probability of Fixation When Population Size and the Strength of Selection Change Over Time

D. Waxman

Genetics 188: 907-913 (2011)

Centre for Computational Systems Biology
Fudan University
Shanghai
People's Republic of China

and

Faculty of Science and Engineering
University of Brighton
Brighton
United Kingdom

The fixation probability is determined when population size and selection change over time, and differs from Kimura's result, with long term implications for a population. It is found that changes in population size are not equivalent to the corresponding changes in selection, and can result in less drift than anticipated.